Table 1 Proteins differentially expressed in severe COVID-19 patients with adverse prognosis, compared to favorable prognosis.

From: Identification of serum prognostic biomarkers of severe COVID-19 using a quantitative proteomic approach

Protein accessions

Genes

Protein descriptions

#Detected peptides

p-value (− log)

Difference [adverse/favorable] (log2)

Increased protein

P02144

MB

Myoglobin

3

3.646

4.161

P36222

CHI3L1

Chitinase-3-like protein 1

5

3.433

3.690

P05164

MPO

Myeloperoxidase

7

3.363

1.725

Q9Y279

VSIG4

V-set and immunoglobulin domain-containing protein 4

2

3.185

2.147

P04275

VWF

von Willebrand factor

56

2.885

1.117

Q8WVN6

SECTM1

Secreted and transmembrane protein 1

1

2.724

2.690

Q8TF65

GIPC2

PDZ domain-containing protein GIPC2

1

2.526

2.356

P80188

LCN2

Neutrophil gelatinase-associated lipocalin

6

2.365

1.721

P01034

CST3

Cystatin-C

9

2.258

1.431

Q9NPY3

CD93

Complement component C1q receptor

3

2.232

3.348

P10451

SPP1

Osteopontin

5

2.232

2.321

P28799

GRN

Granulins

4

2.168

1.079

P07858

CTSB

Cathepsin B

3

2.146

1.063

Q15904

ATP6AP1

V-type proton ATPase subunit S1

1

2.106

1.252

P24592

IGFBP6

Insulin-like growth factor-binding protein 6

3

2.099

1.276

P08670

VIM

Vimentin

6

2.060

2.112

Decreased protein

P35858

IGFALS

Insulin-like growth factor-binding protein complex acid labile subunit

24

6.068

− 1.829

P17936

IGFBP3

Insulin-like growth factor-binding protein 3

9

3.981

− 1.648

P02766

TTR

Transthyretin

17

3.832

− 1.002

P02654

APOC1

Apolipoprotein C-I

13

3.654

− 1.378

P02655

APOC2

Apolipoprotein C-II

3

3.399

− 1.567

P02656

APOC3

Apolipoprotein C-III

8

3.263

− 1.208

Q92954

PRG4

Proteoglycan 4

17

2.930

− 1.267

P35542

SAA4

Serum amyloid A-4 protein

5

2.621

− 1.003

P53367

ARFIP1

Arfaptin-1

1

2.407

− 1.825

P55056

APOC4

Apolipoprotein C-IV

5

2.206

− 1.291

O95445

APOM

Apolipoprotein M

5

2.139

− 1.363

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