Figure 1

PEA samples. (a, b) Specimens collected during PEA from CTEPH patients were stained by hematoxylin and eosin and stained for elastin by orcein stain. (c) PEA samples presented an intact endothelium as shown by endothelial markers CD31 and vWF, an enlarged α-SMA negative neointima and an α-SMA positive organized media. (d) PEA samples showed the presence of mature microvessels. (E–f) Coagulant material showed a fibrous structure lacking cells.