Table 2 Dosimetric parameters and MUs of VMAT plans with intersection angle of two collimators (Δθ) changing from 20° to 90°, along with their Friedman test results.

From: Optimization of collimator angles in dual-arc volumetric modulated arc therapy planning for whole-brain radiotherapy with hippocampus and inner ear sparing

 

Parameter

Result for VMAT with collimator angles θ1/θ2 a

p-value

350°/10°

350°/30°

350°/45°

350°/60°

350°/80°

PTV

CI

0.848 ± 0.009

0.853 ± 0.007

0.856 ± 0.007

0.858 ± 0.004

0.857 ± 0.008

0.002*

HI

0.259 ± 0.023

0.212 ± 0.016

0.202 ± 0.016

0.199 ± 0.012

0.194 ± 0.019

 < 0.001*

Hippocampus

D100% (cGy)

929.7 ± 40.1

891.1 ± 32.8

884.2 ± 25.1

880.5 ± 31.7

878.8 ± 29.2

 < 0.001*

Dmax (cGy)

1507.2 ± 105.6

1433.0 ± 77.7

1422.0 ± 65.7

1434.2 ± 76.7

1412.7 ± 79.3

 < 0.001*

Dmean (cGy)

1103.3 ± 43.3

1056.5 ± 31.0

1053.8 ± 27.6

1049.6 ± 29.7

1043.3 ± 30.3

 < 0.001*

Inner ear

Dmean (cGy)

1437.6 ± 40.3

1433.0 ± 20.1

1429.5 ± 30.0

1427.4 ± 29.8

1427.3 ± 29.1

0.008*

Lens

Dmax (cGy)

705.3 ± 29.3

697.2 ± 33.3

705.5 ± 32.6

703.6 ± 24.7

702.4 ± 38.1

0.699

Optical nerve

Dmax (cGy)

3143.5 ± 156.3

3106.8 ± 118.2

3175.1 ± 40.4

3123.6 ± 103.1

3087.3 ± 127.0

0.053

Eye

Dmean (cGy)

970.9 ± 37.5

943.2 ± 18.3

934.0 ± 17.6

930.5 ± 11.6

921.0 ± 20.9

 < 0.001*

Monitor Unit

MU

1073.6 ± 118.8

929.5 ± 44.6

908.7 ± 33.9

900.6 ± 28.5

899.5 ± 28.2

 < 0.001*

  1. aθ1 and θ2 indicate the collimator angles of arc 1 and arc 2, respectively.
  2. *Statistically significant (p < 0.05).