Table 3 Dosimetric parameters and MUs of Δθ = 90° plans, along with their Friedman test results.

From: Optimization of collimator angles in dual-arc volumetric modulated arc therapy planning for whole-brain radiotherapy with hippocampus and inner ear sparing

 

Parameter

Result for VMAT with collimator angles θ1/θ2 a

p-value

280°/10°

300°/30°

315°/45°

330°/60°

350°/80°

PTV

CI

0.859 ± 0.006

0.859 ± 0.008

0.858 ± 0.007

0.855 ± 0.007

0.857 ± 0.008

0.501

HI

0.189 ± 0.013

0.193 ± 0.013

0.189 ± 0.013

0.194 ± 0.011

0.194 ± 0.019

0.289

Hippocampus

D100% (cGy)

879.4 ± 34.5

873.5 ± 27.1

872.2 ± 28.2

869.8 ± 31.3

878.8 ± 29.2

0.112

Dmax (cGy)

1415.1 ± 71.1

1432.9 ± 69.6

1411.6 ± 81.8

1415.8 ± 65.5

1412.7 ± 79.3

0.074

Dmean (cGy)

1041.7 ± 29.8

1045.4 ± 27.5

1039.6 ± 31.0

1041.6 ± 30.8

1043.3 ± 30.3

0.412

Inner ear

Dmean (cGy)

1411.0 ± 56.0

1412.6 ± 31.1

1407.8 ± 38.1

1403.5 ± 49.4

1427.3 ± 29.1

0.106

Lens

Dmax (cGy)

669.3 ± 26.1

684.6 ± 20.4

683.9 ± 24.5

698.5 ± 27.8

702.4 ± 38.1

0.001*

Optical nerve

Dmax (cGy)

3106.7 ± 87.2

3180.2 ± 55.6

3180.7 ± 96.1

3171.5 ± 63.8

3087.3 ± 127.0

0.001*

Eye

Dmean (cGy)

919.4 ± 22.8

922.8 ± 13.9

918.2 ± 21.0

925.0 ± 9.4

921.0 ± 20.9

0.421

Monitor unit

MU

905.2 ± 37.5

878.4 ± 44.4

878.5 ± 36.7

881.3 ± 36.7

899.5 ± 28.2

0.003*

  1. aθ1 and θ2 indicate the collimator angles of arc 1 and arc 2, respectively.
  2. *Statistically significant (p < 0.05).