Figure 6

Extended pathway analysis of proteins associated with vascular actions of the proteins most important for the separation before (baseline) and after glucose provocation using the STRING database. Vascular pathways highlighted: red = vasodilation, blue = regulation of cellular response to insulin stimulus, green = regulation of blood vessel diameter, yellow = positive regulation of nitric oxide biosynthetic process, turquoise = regulation of vasoconstriction, orange = vasoconstriction, purple = regulation of tube diameter, brown = regulation of blood pressure. PPI enrichment was < 1.0E−16. Proteins involved in vascular pathways: AGT = Angiotensinogen, KNG = Kininogen-1, AHSG = Alpha-2-HS-glycoprotein, HBB = Hemoglobin subunit beta, ACE = Angiotensin converting enzyme, REN = Renin, BDKRB2 = B2 bradykinin receptor.