Figure 2 | Scientific Reports

Figure 2

From: Three-dimensional culture method enhances the therapeutic efficacies of tonsil-derived mesenchymal stem cells in murine chronic colitis model

Figure 2

Expression of cytokines in 3D-cultured TMSCs. The expression of anti-inflammatory cytokines, including IL-10 and TSG-6, were significantly higher in 3D-cultured TMSCs than in 2D-cultured TMSCs as analyzed using qRT-PCR (*P < 0.005). 3D, three-dimensional; TMSCs, tonsil-derived mesenchymal stem cells; IL-10, interleukin 10; TSG-6, tumor necrosis factor-stimulated gene 6; qRT-PCR, quantitative reverse transcription quantitative polymerase chain reaction; CXCR4, C-X-C motif chemokine receptor 4; SDF-1, stromal cell-derived factor 1; TGF-β, transforming growth factor β; IDO-1, indoleamine 2,3-dioxygenase 1; VEGF, vascular endothelial growth factor; BCL-2, B-cell CLL/lymphoma 2; BAX, BCL2 associated X.

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