Figure 4 | Scientific Reports

Figure 4

From: Three-dimensional culture method enhances the therapeutic efficacies of tonsil-derived mesenchymal stem cells in murine chronic colitis model

Figure 4

Weight recovery after treatment with 3D-cultured TMSCs. Body weight loss in the 3D-TMSC-treated group was significantly mitigated when compared with that in the DSS + PBS, the DSS + HEK and 2D-TMSC-treated groups. *On day 18, the body weight loss in the 3D-TMSC-treated group was lower than that in the DSS + PBS (P < 0.001), the DSS + HEK (P = 0.188), and 2D-TMSC-treated groups (P = 0.005). **On day 30, the body weight loss in the 3D-TMSC-treated group was significantly lower than that in the DSS + PBS (P = 0.001), the DSS + HEK (P = 0.027), and 2D-TMSC-treated groups (P = 0.005). 3D, three-dimensional; 2D, two-dimensional; TMSCs, tonsil-derived mesenchymal stem cells; DSS, dextran sulfate sodium; PBS, phosphate-buffered saline; HEK, human embryonic kidney.

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