Figure 5 | Scientific Reports

Figure 5

From: Alveolar socket healing in 5-lipoxygenase knockout aged female mice treated or not with high dose of zoledronic acid

Figure 5

Immunolabeling and quantification of 5LO + cells at 21 days post tooth extraction in WT C vs. WT ZL. Aged 129 Sv WT female mice received IP injections of 0.9% saline solution (C) or 250 μg/Kg (ZL groups) once a week, and upper right incisor were extracted at 4 week of each treatment. (A) Representative transversal sections from the central area of alveolar sockets stained for 5LO + cells in WT C and WT ZL group. (A’) Quantitative and comparative analysis of detached 5LO + cells in WT C vs. Scale bar 30 µm. WT ZL mice at 21 days post-extraction. Results are presented as the means (± SD) of area density (%). Symbol * indicates a statistically significant difference between groups (p < 0.05). DAB chromogen and counterstained with Fast green.

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