Figure 4

Sham-corrected effect of TBS. (A) Left and Right Panel: Group-averaged MEP percentage change from baseline at each time point for each visit with sham TBS subtracted out (from left to right: iTBS and cTBS, respectively). Error bars denote ×2 standard error of the mean. Brackets indicate a significant difference (i.e. p < 0.05) between a TBS protocol at V1 from baseline (i.e. 0, indicated by grey dotted line). (B) Left and Right Panel: Individual-level scatter plots for each TBS protocol between repeat visits with sham subtracted out (from left to right: iTBS and cTBS, respectively). On the x-axis is the participant’s response at V1 for that TBS protocol averaged across all time points and on the y-axis their response at V2 to that TBS protocol averaged across all time points with the equivalent sham responses subtracted out. Fit lines denote least squares. Abbreviations: Diff from Sham - Difference from sham, MEP %Δ to Base—motor evoked potential percentage change to baseline.