Table 2 Diagnostic performance of VCTE for advanced fibrosis and cirrhosis.

From: Combination of FIB-4 with ultrasound surface nodularity or elastography as predictors of histologic advanced liver fibrosis in chronic liver disease

 

AF(F3-F4)

(LSM ≥ 9.6 kPa)

Cirrhosis (F4)

(LSM ≥ 10.2 kPa)

Sensitivity

78.9%

85.1%

Specificity

88.7%

80.0%

PPV

91.5%

76.0%

NPV

73.3%

87.8%

AUROC (95% CI)

0.89 (0.84–0.94)

0.89 (0.84–0.94)

  1. AF, advanced fibrosis; AUROC, area under receiver operating characteristic curve; CI, confidence interval; LSM, liver stiffness measurement; NPV, negative predictive value; PPV, positive predictive value; VCTE, vibration controlled transient elastography.
Back to article page