Table 1 Genomic loci showing, at a minimum, suggestive association with ΔSi and baseline Si.
SNP | Chr | Location (bp) | P | Gene symbol | Gene mapping | Gene location (bp) |
|---|---|---|---|---|---|---|
Delta Si | ||||||
rs4815227 | 20 | 2441096 | 4.50E−07 | TGM6 | Positional | 2380908–2432753 |
rs12449918 | 17 | 15392862 | 1.63E−06 | – | – | – |
rs6799845 | 3 | 172873569 | 1.86E−06 | SPATA16 | Positional | 172889357–173141268 |
rs9211a | 3 | 12898047 | 2.10E−06 | IQSEC1 | Positional | 12897043–13282998 |
– | – | – | LOC105376955 | Positional | 12882360–12885099 | |
– | – | – | RP11-767C1.2 | Skeletal muscle eQTL | 12832219–12832728 | |
– | – | – | CAND2 | Skeletal muscle eQTL | 12796472–12871916 | |
rs14191a | 3 | 12898847 | 2.13E−06 | RP11-767C1.2 | Skeletal muscle eQTL | 12832219–12832728 |
– | – | – | CAND2 | Skeletal muscle eQTL | 12796472–12871916 | |
– | – | – | IQSEC1 | Positional | 12897043–13282998 | |
– | – | – | LOC105376955 | Positional | 12882360–12885099 | |
rs2600330 | 3 | 12926604 | 4.52E−06 | IQSEC1 | Positional | 12897043–13282998 |
rs7722673 | 5 | 168417231 | 7.23E−06 | WWC1 | Positional | 168292060–168472303 |
rs7595372 | 2 | 24409253 | 7.45E−06 | FAM228A | Skeletal muscle eQTL | 24175069–24200849 |
rs969863 | 12 | 97202907 | 7.48E−06 | – | – | – |
rs422455 | 16 | 83729855 | 9.51E−06 | CDH13 | Positional | 82626794–83796610 |
Baseline Si | ||||||
rs11622678* | 14 | 73655058 | 3.79E−08 | PNMA1 | Skeletal muscle eQTL | 73711783–73714372 |
– | – | – | RP3-414A15.10 | Skeletal muscle eQTL | 73616700–73633941 | |
– | – | – | DNAL1 | Positional | 73644875–73703728 | |
– | – | – | RP3-414A15.2 | Skeletal muscle eQTL | 73530152–73530610 | |
rs10936174 | 3 | 159198318 | 3.07E−07 | IQCJ | Positional | 159069252–159266307 |
– | – | – | IQCJ-SCHIP1 | Positional | 159069252–159897366 | |
rs7524898 | 1 | 84167162 | 2.24E−06 | PRKACB | Positional | 84077975–84238498 |
rs10107799 | 8 | 6102222 | 3.07E−06 | – | – | – |
rs7653174 | 3 | 159120808 | 3.13E−06 | IQCJ | Positional | 159069252–159266307 |
– | – | – | IQCJ-SCHIP1 | Positional | 159069252–159897366 | |
rs205666 | 21 | 18120899 | 6.27E−06 | CHODL | Positional | 17819595–18267373 |
rs9511351b | 13 | 24575137 | 8.56E−06 | LOC101927375 | Positional | 24541663–24567321 |
rs9553347b | 13 | 24557233 | 8.56E−06 | LOC105370295 | Positional | 24538602–24541913 |
– | – | – | LOC101927375 | Positional | 24541663–24567321 | |
