Figure 4
From: A novel method for liquid-phase extraction of cell-free DNA for detection of circulating tumor DNA
Results of PHASIFY ENRICH against QCNA. (a) A violin plot of total DNA recovery from 1 mL of plasma from QCNA and PHASIFY ENRICH. Median bars are shown as solid black lines. Median DNA recovery for QCNA and PHASIFY ENRICH are 17 ng and 11 ng, respectively (35% decrease). (b) Sensitivity and specificity values of PHASIFY ENRICH and QCNA against tissue genotyping. (c) A violin plot of total mutant copies recovered from QCNA and PHASIFY ENRICH out of the samples in which both kits detected mutations (n = 28). Median bars are shown as solid black lines. Median mutant copy recovery for QCNA and PHASIFY ENRICH are 85 copies and 215 copies, respectively (153% increase).
