Figure 5
Early endosome/lysosome in VE cells of E5.5 embryos. Localisation of the early endosome marker, SNX1 (red), in wild-type (a, and boxed regions 1 to 3) (n = 3) and Atp6v0c mutant embryos (b, and boxed regions 4 to 6) (n = 4). VE cells were labelled with GATA6 (blue). Localisation of the recycling endosome marker, RAB4 (red), and Lamp2 (green) in wild-type (c–f) (n = 9) and Atp6v0c mutant embryos (g–j) (n = 4). Localisation of the recycling endosome marker, RAB11 (red), and Lamp2 (green) in wild-type (k–n) (n = 18) and Atp6v0c mutant embryos (o–r) (n = 13). Scale bars are indicated in each panel.
