Figure 5 | Scientific Reports

Figure 5

From: Leu-to-Phe substitution at prM146 decreases the growth ability of Zika virus and partially reduces its pathogenicity in mice

Figure 5

In vitro growth of the point mutant rPRVABC59 prML146F. (a) Schematic representation of the mutant rPRVABC59 prML146F. (b) Focus phenotypes of rPRVABC59 and rPRVABC59 prML146F in Vero cells. (c) Growth curves of the point mutants rPRVABC59 prML146F and rNIID123 prMF146L in Vero cells. Cells were inoculated with the viruses at an MOI of 0.01 ffu/cell. Means ± standard deviations of three independent experiments are shown.

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