Figure 10

The correlation between different physicochemical parameters and genomic functional potentials of the AD microbiomes. The numbers display the Spearman’s correlation coefficient (r). Blue and red indicate positive and negative correlation, respectively. The color density, circle size, and numbers reflect the scale of correlation. *Significant level (*p < 0.05; **p < 0.01; ***p < 0.001). (A) Correlation analysis of different physicochemical parameters and SEED subsystems. (B) Correlation analysis of different physicochemical parameters and KEGG pathways. The R packages, Hmisc (https://cran.r-project.org/web/packages/Hmisc/index.html) and corrplot (https://cran.r-project.org/web/packages/corrplot/vignettes/corrplot-intro.html) were used respectively to analyze and visualize the data.