Table 2 Number of compounds detected in ≥ 3 plasma and marrow samples, and number that were significantly correlated after FDR correction, by class.
N detected | Rho, median (IQR) | N correlateda | p (under-representation) | p (over-representation) | |
|---|---|---|---|---|---|
Total | 661 | 0.62 (0.29–0.83) | 207 | – | – |
Amino acid | 161 | 0.58 (0.32–0.77) | 44 | 0.01 | 0.99 |
Carbohydrate | 21 | 0.28 (0.10–0.45) | 2 | 0.01 | 0.99 |
Cofactor/vitamin | 26 | 0.59 (0.28–0.82) | 9 | 0.57 | 0.43 |
Energy | 7 | − 0.21 (− 0.36–0.57) | 1 | 0.23 | 0.77 |
Lipid | 332 | 0.70 (0.31–0.84) | 142 | 0.99 | < 0.001 |
Nucleotide | 30 | 0.49 (0.32–0.69) | 6 | 0.05 | 0.95 |
Peptide | 19 | 0.33 (0.14–0.55) | 2 | 0.02 | 0.98 |
Xenobiotic | 65 | 0.77 (0.43–0.90) | 26 | 0.85 | 0.15 |
