Table 3 Number of compounds detected in ≥ 3 plasma and CSF samples, and number that were significantly correlated after FDR correction, by class.
N detected | Rho, median (IQR) | N correlateda | p (under-representation) | p (over-representation) | |
|---|---|---|---|---|---|
Total | 328 | 0.37 (0.07–0.70) | 40 | – | – |
Amino acid | 133 | 0.45 (0.13–0.72) | 15 | 0.41 | 0.59 |
Carbohydrate | 20 | 0.15 (− 0.08–0.57) | 3 | 0.79 | 0.22 |
Cofactor/vitamin | 15 | 0.48 (0.11–0.74) | 3 | 0.91 | 0.10 |
Energy | 8 | 0.17 (0.08–0.31) | 0 | 0.35 | 0.65 |
Lipid | 71 | 0.28 (− 0.04–0.57) | 5 | 0.09 | 0.91 |
Nucleotide | 31 | 0.31 (0.16—0.46) | 2 | 0.24 | 0.76 |
Peptide | 12 | 0.13 (− 0.28–0.37) | 2 | 0.83 | 0.17 |
Xenobiotic | 38 | 0.76 (0.28–0.94) | 10 | 0.99 | 0.002 |
