Table 3 Results of the analysis treating PFOS and PFOA concentrations as dimensional and categorical measures.

From: Umbilical cord serum concentrations of perfluorooctane sulfonate, perfluorooctanoic acid, and the body mass index changes from birth to 5 1/2 years of age

 

Intercept

Interaction with age

β (SE) p value

β (SE) p value

crude

adjusted

crude

adjusted

Dimensional

PFOS

Overall

− 0.27 (0.14) 0.05

− 0.35 (0.14) 0.01

0.0038 (0.002) 0.08

0.0038 (0.002) 0.09

Boys

0.001 (0.18) > 0.99

− 0.095 (0.19) 0.62

0.0011 (0.003) 0.71

0.0011 (0.003) 0.72

Girls

− 0.67 (0.2) 0.001

− 0.69 (0.2) 0.001

0.0081 (0.003) 0.015

0.0082 (0.003) 0.014

PFOA

Overall

− 0.22 (0.12) 0.07

− 0.26 (0.13) 0.05

0.0051 (0.002) 0.01

0.0051 (0.002) 0.01

Boys

0.15 (0.18) 0.4

0.16 (0.19) 0.41

− 0.001 (0.003) 0.72

− 0.001 (0.003) 0.74

Girls

− 0.59 (0.17) < 0.001

− 0.62 (0.18) < 0.001

0.011 (0.003) < 0.001

0.011 (0.003) < 0.001

Categorical

PFOS

Overall

Low

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

Middle

0.042 (0.071) 0.55

0.022 (0.07) 0.75

− 0.0001 (0.0012) 0.91

− 0.0001 (0.0012) 0.92

High

− 0.16 (0.075) 0.03

− 0.175 (0.076) 0.02

0.0029 (0.0012) 0.02

0.0029 (0.0012) 0.02

Boys

Low

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

Middle

0.14 (0.10) 0.16

0.11 (0.1) 0.28

− 0.0022 (0.0017) 0.2

− 0.0022 (0.0017) 0.2

High

− 0.021 (0.11) 0.84

− 0.03 (0.11) 0.75

0.0012 (0.0017) 0.49

0.0012 (0.0017) 0.49

Girls

Low

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

Middle

− 0.066 (0.096) 0.49

− 0.083 (0.094) 0.38

0.0019 (0.0016) 0.24

0.002 (0.0016) 0.23

High

− 0.33 (0.10) 0.002

− 0.34 (0.11) 0.002

0.005 (0.0018) 0.005

0.005 (0.0018) 0.004

PFOA

Overall

Low

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

Middle

− 0.091 (0.072) 0.21

− 0.069 (0.072) 0.34

0.0044 (0.0012) < 0.001

0.0044 (0.0012) < 0.001

High

− 0.16 (0.074) 0.03

− 0.18 (0.078) 0.02

0.0038 (0.0012) 0.002

0.0039 (0.0012) 0.002

Boys

Low

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

Middle

0.0049 (0.10) 0.96

0.026 (0.1) 0.8

0.0029 (0.0017) 0.08

0.0029 (0.0017) 0.08

High

0.044 (0.10) 0.67

0.03 (0.11) 0.79

0.0003 (0.0017) 0.88

0.0003 (0.0017) 0.86

Girls

Low

0.00 (reference)

0.00 (Reference)

0.00 (Reference)

0.00 (Reference)

Middle

− 0.19 (0.098) 0.06

− 0.17 (0.1) 0.1

0.0059 (0.0016) < 0.001

0.0059 (0.0016) < 0.001

High

− 0.41 (0.1) < 0.001

− 0.41 (0.11) < 0.001

0.0078 (0.0017) < 0.001

0.0079 (0.0017) < 0.001

  1. Controlling covariates: maternal age at delivery, maternal BMI before pregnancy, maternal education, household income, maternal smoking during pregnancy, parity, gestational age, and duration of breast feeding. NB: SE denotes standard error, PFOS denotes perfluorooctane sulfonate, PFOA denotes perfluorooctanoic acid.