Figure 4
Weighted gene coexpression network analysis (WGCNA) of autosomal aneuploidy Drosophila. (A) Dot and line plots showing the eigengene expression (mean ± 95% confidence interval) of each gene-coexpression module by genotypes in autosomal aneuploidy groups. The modules are ordered according to the number of genes they contain. F, female; 2LF, trisomy 2L female; MSL2-2LF, MSL2-trisomy 2L female; M, male; 2LM, trisomy 2L male; MSL2-2LM, MSL2-trisomy 2L male. (B) Top two GO term enrichments for each module. (C) Heatmap showing the expression level of genes in every coexpression module in autosomal aneuploidy groups. Each column is a biological repetition and each row is a gene. Hierarchical clustering is carried out only within the module and genotype groups. The horizontal dotted lines divide the four largest modules. The 10,000 genes with the highest average expression were involved in the coexpression network analysis. Gray modules are not considered in the plots because they represent unclustered genes.
