Table 2 Biomarkers to differentiate between infection vs inflammation in severe alcoholic hepatitis.

From: Utility of neutrophil CD64 in distinguishing bacterial infection from inflammation in severe alcoholic hepatitis fulfilling SIRS criteria

Groups

N

Mean

SD

P value

nCD64%

Infection

58

76.66

22.60

 < 0.001

Non- Infection

70

16.02

18.96

MFI of nCD64

Infection

58

1431

359

 < 0.001

Non- Infection

70

853

257

CRP (mg/dl)

Infection

58

6.20

4.84

 < 0.001

Non- Infection

70

3.11

3.57

ESR (mm 1st hour)

Infection

58

91.18

37.59

 < 0.001

Non- Infection

70

63.06

41.46

Serum Procalcitonin (ng/ml)

Infection

58

0.438

0.240

 < 0.001

Non- Infection

70

0.185

0.128

TLC (/µl)

Infection

58

11,108.19

6911.99

0.001

Non- Infection

70

7402.50

4166.63

  1. Data is presented as mean ± SD. Independent samples t test used. #Presented in median (interquartile range) and compared by Mann Whitney U test used. p < 0.05 significant.
  2. nCD64% Neutrophils CD64 expression in percentage, MFI Mean fluorescence intensity, CRP C-reactive protein, ESR erythrocyte sedimentation rate, TLC total leukocyte count.
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