Figure 3
Effect of the immunomodulator over circulating neutrophil concentration of puppies affected by CPE. (A) Circulating neutrophils in surviving dogs (day 2-critical day) and (B) circulating neutrophils in surviving dogs (day 4-recovery day), statistical differences on days 2 and 4 are due to lower neutrophil concentrations in CT + I than in CT + V. Mann–Whitney test was done. Each dot represents a puppy. Median ± 5–95% confidence interval. (C) Neutrophil concentrations on day 0, critical day (2) and recovery day (4) in the CT + V group. Neutrophil concentrations on day 4 are responsible for statistical differences. (D) Circulating neutrophils on day 0, critical day (2) and recovery day (4), reduction in neutrophils on day two results in statistical differences in CT + I. Each dot represents a puppy. Kruskal–Wallis test and Dunn's post-hoc test were carried out. *P ≤ 0.05, **P ≤ 0.01. CT conventional treatment, I immunomodulatory, V vehicle.
