Figure 4
Effect of the immunomodulator over the concentration of circulating lymphocytes of puppies affected by CPE. (A) Circulating lymphocytes in surviving dogs on a critical day (day 2) and (B) circulating lymphocytes in surviving dogs on recovery day (day 4); there are no statistical differences between groups on day 4; the difference on day 2 is due to the lower lymphocyte values in CT + I vs CT + V. Mann–Whitney test was performed. Each dot represents a puppy. Median ± 5–95% confidence interval. (C) Lymphocyte concentrations on day 0, critical day (2), and recovery day (4) in the CT + V group. Lymphocyte concentrations do not show statistical differences at any time evaluated. Kruskal–Wallis test and Dunn's post-hoc test were done. Each dot represents a puppy. (D) Circulating lymphocytes in CT + I group, this group showed differences in recovery time due to an increase in lymphocytes as compared with basal measurement and day 2. One-way ANOVA, Tukey's post-hoc test. Each dot represents a puppy. Mean ± SD. *P ≤ 0.05. CT conventional treatment, I immunomodulatory, V vehicle.
