Figure 3
In vitro experiment designated for showing copper extraction due to dialysis with Chitosan@DOTAGA. (A) Schematic representation of the experiment. (B) Amount of copper extracted (µg/h) from the copper II solution with (red) or without (black) Chitosan@DOTAGA according to increased blood flow rates (QB) (mL/min). (C) Copper concentration in the copper solution before dialysis and in the effluent (ppb) with (red) or without (black) Chitosan@DOTAGA with QB = 20, 40, 80 and 100 mL/min and QD (dialysate flow rate) = 250 mL/h. (D) Percentage ratio of copper extraction capacity between Chitosan@DOTAGA and the Hemosol B0 alone according to QB (mL/min). The linear regression slope equation ‘y = b + ax’ is presented along with the correlation coefficient (R) and the Pearson correlation p value (p). (E) Amount of copper extracted (µg/h) from the copper solution with (red) or without (black) Chitosan@DOTAGA according to QD (mL/h). Stars indicates significant differences according to non-parametric Kruskal–Wallis tests (NS: non-significant, *: p value < 0.05, **: p value < 0.01, ***: p value < 0.001).
