Figure 5

Skin T-cells derived from patients with cutaneous vasculitis proliferate and express Granzyme B. (a) Representative gating strategy of T-cell subsets derived from the skin. (b, c) Representative flow contour plots and frequencies of Ki67⁺cells within (b) CD4⁺ or (c) CD8⁺ T-cell populations in patients with cutaneous vasculitis and healthy donors (HD). (d, e) Representative flow contour plots and frequencies of Ki67⁺ Granzyme B⁺ cells within (d) CD4⁺ or (e) CD8⁺ T-cell populations in patients with cutaneous vasculitis and HD. Data indicate mean ± SEM. *p < 0.05.