Figure 2
Effect of compound mixtures containing lomustine on the viability of GB cell lines. pIC50 values ± standard errors of mean are shown (N ≥ 4) for U-251 MG (a) or T98-G (b) following 48 h treatment. The further each column protrudes to the right, the more efficient is the corresponding mixture. In brackets, the molar ratios of components in each point of the dose–response curve are listed. The dotted vertical line shows the pIC50 value for lomustine alone. The columns colored in orange indicate mixtures for which the pIC50 value was significantly higher than the pIC50 value of either component within the given mixture (P < 0.05).
