Table 4 GO and pathway analysis using the candidate genes associated with the multifocal and diffuse lesions.

From: Identification of loci associated with pathological outcomes in Holstein cattle infected with Mycobacterium avium subsp. paratuberculosis using whole-genome sequence data

Phenotype

ID

Description

P adjust

Genes

Genes ratio

Multifocal

GO:0045095

Keratin filament

6.816E−13

KRT73/KRT72/KRT74/KRT5/KRT75/KRT83/KRT81/KRT7/KRT80

9/44

GO:0005882

Intermediate filament

1.691E−10

KRT73/KRT72/KRT74/KRT5/KRT6B/KRT75/KRT83/KRT81/KRT7/KRT80

10/44

GO:0045111

Intermediate filament cytoskeleton

4.644E−10

KRT73/KRT72/KRT74/KRT5/KRT6B/KRT75/KRT83/KRT81/KRT7/KRT80

10/44

GO:0099512

Supramolecular fiber

4.389E−07

KRT73/KRT72/KRT74/KRT5/KRT6B/KRT75/KRT83/KRT81/KRT7/KRT80/MYOM1/MYL12A/MYL12B

13/44

GO:0099081

Supramolecular polymer

4.389E−07

KRT73/KRT72/KRT74/KRT5/KRT6B/KRT75/KRT83/KRT81/KRT7/KRT80/MYOM1/MYL12A/MYL12B

13/44

GO:0099513

Polymeric cytoskeletal fiber

1.689E−05

KRT73/KRT72/KRT74/KRT5/KRT6B/KRT75/KRT83/KRT81/KRT7/KRT80

10/44

GO:0099080

Supramolecular complex

2.1E−05

KRT73/KRT72/KRT74/KRT5/KRT6B/KRT75/KRT83/KRT81/KRT7/KRT80/MYOM1/MYL12A/MYL12B

13/44

Diffuse

bta04979

Cholesterol metabolism

0.016505

NCEH1/LDLR/ANGPTL8/ANGPTL4

4/49