Table 5 Prior PAAGES-I → LEFAGES-II regression models with \({N}_{m}\) and \({\mu }_{m}\) added as theorized mediators.

From: Soft tissue radiodensity parameters mediate the relationship between self-reported physical activity and lower extremity function in AGES-Reykjavík participants

 

Fast gait speed (GSF)

Normal gait speed (GSN)

Isometric leg strength (STR)

Timed up-and-go (TUG)

β

SE

p-value

β

SE

p-value

β

SE

p-value

β

SE

p-value

Variable

PAAGES-I

0.1377

0.003

< 0.001

0.1431

0.002

< 0.001

0.0720

0.894

< 0.001

− 0.1118

0.041

< 0.001

\({N}_{m}\)

0.2781

3.9E−4

< 0.001

0.2494

2.8E−4

< 0.001

0.3162

0.126

< 0.001

− 0.0443

0.006

< 0.001

\({\mu }_{m}\)

0.0853

0.002

< 0.001

0.1092

0.001

< 0.001

0.0953

0.522

< 0.001

− 0.1464

0.023

< 0.001

Age

− 0.2716

0.001

< 0.001

− 0.3264

0.001

< 0.001

− 0.1718

0.317

< 0.001

0.2779

0.014

< 0.001

Sex

− 0.1522

0.011

< 0.001

− 0.0261

0.008

0.191

− 0.4192

3.60

< 0.001

− 0.0622

0.162

0.003

BMI

− 0.2853

0.001

< 0.001

− 0.2876

0.001

< 0.001

− 0.0848

0.410

< 0.001

0.2630

0.019

< 0.001

LEFAGES-I

0.0224

0.017

0.166

0.0135

0.017

0.384

0.0104

0.012

0.443

0.0139

0.023

0.399

Prior effect

PAAGES-I

0.1686

0.003

< 0.001

0.1755

0.002

< 0.001

0.1060

0.934

< 0.001

− 0.1406

0.038

< 0.001

% Change

− 18.3%

  

− 18.5%

  

− 32.1%

  

− 20.3%

  
  1. All twelve hypothesis tests surpassed their respective thresholds for HB correction.