Figure 3 | Scientific Reports

Figure 3

From: Defining the kinetic effects of infection with influenza virus A/PR8/34 (H1N1) on sphingosine-1-phosphate signaling in mice by targeted LC/MS

Figure 3

Expression levels of major S1P receptors (a) and transporters (b) in the liver, lung and e-WAT. Mice were intranasally inoculated with PBS alone or PBS comprising PR8 virus (500 PFU), and liver, e-WAT, lung, heart, and aorta samples were collected at 1, 3, and 6 dpi. Expressions of target genes normalized with that of 18S are presented as fold changes relative to those of the control mice at each time point. Bars represent means ± SEM of 7 or 8 (liver) or 3 or 4 (e-WAT) animals. White and black bars indicate data from control and PR8 virus-infected mice, respectively; *p < 0.05, 2way-ANOVA on ddCt, control vs. PR8 virus-infected mice at each time point.

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