Table 2 Association of ocular surface immune cell subset proportions with corneal keratometry and pachymetry indices of KC patients.

From: Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile

Proportion of ocular surface immune cell subsets

K1 (D)

K2 (D)

Kmean (D)

Kmax (D)

CCT (μm)

TCT (μm)

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

Total leukocytes

CD45+ cells

− 0.018

0.901

0.082

0.568

0.035

0.809

0.110

0.441

0.088

0.541

0.075

0.600

Neutrophil subsets

CD66bTotal cells

− 0.037

0.794

− 0.044

0.758

− 0.047

0.745

− 0.015

0.919

0.156

0.273

0.124

0.386

CD66bLow cells

0.203

0.152

0.137

0.339

0.171

0.229

0.095

0.508

− 0.111

0.438

− 0.109

0.447

CD66bHigh cells

− 0.257

0.069

− 0.240

0.090

− 0.252

0.074

− 0.210

0.139

0.336

0.016

0.312

0.026

CD66bHigh/CD66bLow cells ratio

− 0.236

0.096

− 0.218

0.125

− 0.227

0.110

− 0.163

0.254

0.254

0.073

0.274

0.052

Macrophages

CD163+ cells

− 0.094

0.512

− 0.120

0.401

− 0.101

0.481

− 0.134

0.349

0.082

0.565

0.081

0.574

Natural killer (NK) cell subsets

CD56Total cells

0.014

0.923

− 0.001

0.995

0.012

0.933

− 0.005

0.974

− 0.238

0.092

− 0.236

0.095

CD56Low cells

− 0.063

0.662

− 0.067

0.643

− 0.063

0.662

− 0.066

0.643

− 0.190

0.182

− 0.190

0.181

CD56High cells

0.130

0.364

0.046

0.749

0.098

0.496

0.052

0.715

− 0.089

0.535

− 0.072

0.617

CD56High/CD56Low NK cells ratio

0.171

0.235

0.168

0.244

0.172

0.233

0.144

0.320

− 0.139

0.337

− 0.149

0.302

CD66b+/CD56+ cells ratio

− 0.036

0.802

− 0.034

0.813

− 0.043

0.762

− 0.007

0.960

0.199

0.162

0.169

0.235

T cell subsets

CD3+T cells

0.271

0.055

0.273

0.053

0.277

0.049

0.221

0.119

− 0.272

0.054

− 0.313

0.026

CD3+CD56+ T (NKT) cells

0.016

0.913

0.057

0.700

0.080

0.588

0.044

0.764

− 0.101

0.493

− 0.093

0.532

CD3+γδTCR+ T cells

0.345

0.013

0.324

0.020

0.344

0.014

0.254

0.072

− 0.307

0.029

− 0.300

0.032

  1. r = Spearman rank correlation coefficient.