Table 3 Association of tear fluid soluble factor levels with corneal keratometry and pachymetry indices of KC patients.

From: Keratoconus patients exhibit a distinct ocular surface immune cell and inflammatory profile

Soluble factors

K1 (D)

K2 (D)

Kmean (D)

Kmax (D)

CCT (um)

TCT (um)

r

P value

r

P value

r

P value

r

P value

r

P value

r

P value

IL-10

0.492

0.001

0.513

0.001

0.504

0.001

0.518

0.001

− 0.300

0.057

− 0.321

0.041

IL-12p70

0.190

0.235

0.264

0.096

0.223

0.161

0.291

0.065

− 0.014

0.929

− 0.031

0.846

IL-13

0.334

0.033

0.334

0.033

0.331

0.034

0.325

0.038

− 0.120

0.456

− 0.128

0.427

IL-17A

0.307

0.051

0.340

0.029

0.330

0.035

0.345

0.027

− 0.110

0.493

− 0.140

0.383

TNFα

0.388

0.012

0.402

0.009

0.404

0.009

0.410

0.008

− 0.211

0.186

− 0.245

0.122

sTNFRI

− 0.306

0.052

− 0.325

0.038

− 0.317

0.043

− 0.306

0.051

0.184

0.249

0.211

0.185

Eotaxin

0.229

0.150

0.303

0.054

0.260

0.100

0.331

0.034

− 0.083

0.606

− 0.093

0.564

NGAL

− 0.242

0.127

− 0.316

0.044

− 0.273

0.084

− 0.313

0.046

0.181

0.258

0.200

0.210

EPO

− 0.207

0.194

− 0.270

0.088

− 0.236

0.137

− 0.321

0.041

0.163

0.309

0.183

0.253

sP-selectin

0.424

0.006

0.385

0.013

0.391

0.012

0.382

0.014

− 0.240

0.130

− 0.234

0.141

TGFβ1

0.201

0.208

0.279

0.077

0.236

0.138

0.301

0.056

− 0.032

0.841

− 0.054

0.739

  1. r = Spearman rank correlation coefficient.