Table 4 Absolute and relative frequencies of dosage adjustments from standard to reduced dose and from reduced to standard dose at first and subsequent prescriptions.
12 months N° (%) | 24 months N° (%) | 36 months N° (%) | Overall | |
---|---|---|---|---|
Switches form standard to reduced dose | ||||
Dabigatran (53,689) | 1691 (3.15%) | 1604 (2.99%) | 1567 (2.92%) | 4862 (9.06%) |
Rivaroxaban (50,737) | 2291 (4.52%) | 2259 (4.45%) | 2144 (4.23%) | 6694 (13.19%) |
Apixaban (38,966) | 1662 (4.27%) | 1536 (3.94%) | 1422 (3.65%) | 4620 (11.86%) |
Switches form reduced to standard dose | ||||
Dabigatran (53,689) | 805 (1.5%) | 660 (1.23%) | 646 (1.2%) | 2111 (3.93%) |
Rivaroxaban (50,737) | 614 (1.21%) | 621 (1.22%) | 722 (1.42%) | 1957 (3.86%) |
Apixaban (38,966) | 707 (1.81%) | 761 (1.95%) | 731 (1.88%) | 2199 (5.64%) |