Table 3 Changes in body temperature during a hypercapnic gas challenge and upon return to room-air in male and female wild-type and endothelial nitric oxide synthase knock-out mice.

From: Ventilatory responses during and following hypercapnic gas challenge are impaired in male but not female endothelial NOS knock-out mice

Sex

Group

Pre

Arithmetic changes in body temperature (°C)

Hypercapnia

Room-air

5 min

15 min

5 min

15 min

Male

WT

36.5 Âħ 0.1

 − 0.07 Âħ 0.08

 − 0.02 Âħ 0.07

 + 0.07 Âħ 0.06

 + 0.00 Âħ 0.07

eNOS-/-

36.6 Âħ 0.1

 + 0.05 Âħ 0.12

 − 0.08 Âħ 0.12

 − 0.02 Âħ 0.08

 + 0.05 Âħ 0.06

Female

WT

36.7 Âħ 0.1

 − 0.07 Âħ 0.11

 + 0.08 Âħ 0.08

 − 0.05 Âħ 0.12

 + 0.02 Âħ 0.06

eNOS-/-

36.8 Âħ 0.1

 − 0.03 Âħ 0.11

 + 0.07 Âħ 0.09

 − 0.03 Âħ 0.09

 − 0.05 Âħ 0.03

  1. The data are presented as mean Âħ SEM. WT, wild-type C57BL6 mice. eNOS-/-, endothelial nitric oxide synthase knock-out mice. There were 6 mice in each group. Note, there were no significant changes in body temperature or any between-group differences at any time point (P > 0.05, for all comparisons).
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