Figure 5
From: Repeated exposure of the oral mucosa over 12 months with cold plasma is not carcinogenic in mice
Frequencies and size of lesions and squamous cell carcinoma (SCCs). (a) the number of lesion-free and animals across all groups without administration of the co-carcinogen dibenzo(a)pyrene (DBP) indicating an absence of lesions with either of the treatments; (b) the number of lesion-free and animals across all groups with low dose (8 nmol) administration of the co-carcinogen DBP indicating the occurrence of 1–2 lesions or SSCs with either of the treatments; (c) the number of lesion-free and animals across all groups with high dose (24 nmol) administration of the co-carcinogen DBP indicating the occurrence of less than 20% of lesions or SSC-free animals with either of the treatments; (d) summary of results shown as percent histological result per DBP administration and treatment subgroup; (e) violin plots with single data showing the median (full red line) and 25% percentile (dotted red line) suggesting a lesion and SCC-reducing effect of 60 s of kINPen plasma treatment. Statistical analysis was performed using Fisher exact tests (d) and Kruskal–Wallis one-way analysis of variances (e) with p < 0.05 considered to be statistically significant (*); n = 19–26.
