Table 1 Univariate analyses of correlation between clinicopathological features and LLNM in tongue SCC patients with lymph node metastases.

From: Prognostic impact of lingual lymph node metastasis in patients with squamous cell carcinoma of the tongue: a retrospective study

Clinicopathological features

Cervical LNM without LLNM (n = 107)

Cervical LNM and LLNM (n = 21)

P-value

Age

Ā Ā 

0.58*

 < 60Ā years

49

11

Ā 

 > 60Ā years

58

10

Ā 

Sex

Ā Ā 

0.63*

Male

76

16

Ā 

Female

31

5

Ā 

cT

Ā Ā 

0.23*

T1 + T2

80

13

Ā 

T3 + T4

27

8

Ā 

Pathological differentiation

Ā Ā 

0.72*

Well

41

7

Ā 

Moderate

36

9

Ā 

Poor

26

5

Ā 

Unknown

4

0

Ā 

Number of ipsilateral positive nodes

Ā Ā 

 < 0.01*

 < 3

89

11

Ā 

 ≄ 4

18

10

Ā 

Level of ipsilateral positive nodes

Ā Ā 

0.02**

Level I, II, or III

103

17

Ā 

Level IV or V

4

4

Ā 

ENE of ipsilateral positive nodes

Ā Ā 

0.02*

Negative

60

6

Ā 

Positive

47

15

Ā 

Contralateral cervical LNM

Ā Ā 

 < 0.01*

Absence

98

15

Ā 

Presence

9

6

Ā 
  1. SCC squamous cell carcinoma, LNM lymph node metastasis, LLNM lingual lymph node metastasis, ENE extranodal extension.
  2. *Chi-square test.
  3. **Fisher’s exact test. P < 0.05 is considered statistically significant in all analyses.