Figure 2 | Scientific Reports

Figure 2

From: Performances of rapid and connected salivary RT-LAMP diagnostic test for SARS-CoV-2 infection in ambulatory screening

Figure 2

(A) Sensitivity of salivary RT-LAMP evaluated against NP and salivary RT-qPCR Ct values. Ct value cutoffs indicate the infectious status of individuals considered as positive/negative. Dots show sensitivity (%) of RT-LAMP against salivary RT-qPCR (R2 = 0.92). Triangles show sensitivity (%) of salivary RT-LAMP compared to NP RT-qPCR (R2 = 0.61). RT-qPCR, reverse transcription quantitative polymerase chain reaction; RT-LAMP, reverse transcription loop-mediated isothermal amplification; NP, nasopharyngeal; Sal, salivary; Ct, cycle threshold. (B) Comparison of Ct Value between NP and salivary RT-qPCR. Dots represent experimentally measured Ct values of nasopharyngeal (X) and salivary (Y) RT-qPCR. Positive concordant individuals (positive for both NP and salivary RT-qPCR) are in down left white corner . Negative concordant individuals (Ct value ≥ 35 for both NP and salivary RT-qPCR) are in upper right white corner . Discordant results (negative for one specimen and positive for the other in RT-qPCR) are on the grey zones of the graphic (NP+/Sal- ; NP-/Sal+).

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