Table 1 Characteristics of tumor development in zebrafish receiving optic nerve injury (ONI) versus control zebrafish.

From: brca2-mutant zebrafish exhibit context- and tissue-dependent alterations in cell phenotypes and response to injury

 

Ocular tumors

Non-ocular tumors

Total tumors

Location of tumor development (ocular versus non-ocular)

ONI group

45 (37%)

77 (63%)

122

brca2 m/m;tp53 m/m

29 (43%)

39 (57%)

68

tp53 m/m

16 (30%)

38 (70%)

54

Control group

36 (34%)

70 (66%)

106

brca2 m/m;tp53 m/m

23 (42%)

32 (58%)

55

tp53 m/m

13 (25.5%)

38 (74.5%)

51

 

Right/ONI side

Left /non-ONI side

Bilateral

Side of ocular tumor development

ONI group

18 (40%)

19 (42%)

8 (18%)

brca2 m/m;tp53 m/m

13 (45%)

10 (34%)

6 (21%)

tp53 m/m

5 (31%)

9 (56%)

2 (13%)

Control group

17 (47%)

14 (39%)

5 (14%)

brca2 m/m;tp53 m/m

11 (48%)

9 (39%)

3 (13%)

tp53 m/m

6 (46%)

5 (39%)

2 (15%)