Table 3 High versus low doses of steroid replacement therapy in patients with diabetes mellitus (DM)/prediabetes.
From: Prediction of diabetes mellitus induced by steroid overtreatment in adrenal insufficiency
DM/prediabetes No 42 | |||
|---|---|---|---|
Low doses No 18 | High doses No 24 | p | |
Mean ± SD | Mean ± SD | ||
Age (years) | 48.1 ± 14.1 | 53.5 ± 11.1 | 0.167 |
Duration of disease (years) | 16.2 ± 17.9 | 19.3 ± 9.31 | 0.472 |
BMI (Kg/m2) | 27.6 ± 6.65 | 29.5 ± 4.55 | 0.273 |
WC (cm) | 97.9 ± 14.7 | 101 ± 14.2 | 0.505 |
DM/prediabetes No 42 | |||
|---|---|---|---|
Low doses No 18 | High doses No 24 | ||
Subjects (%) | Subjects (%) | ||
Male | 8 (44.4%) | 5 (20.8%) | 0.174 |
Female | 10 (55.6%) | 19 (79.2%) | |
Family history of Diabetes | 7 (38.8%) | 10 (41.6%) | 0.545 |
Arterial hypertension | 3 (16.7%) | 10 (41.6%) | 0.184 |
Hypertriglyceridemia | 5 (27.8%) | 13 (54.1%) | 0.237 |
Hypercholesterolemia | 3 (16.7%) | 6 (25%) | 0.275 |
Visceral obesity | 10 (55.6%) | 22 (91.7%) | 0.158 |
Hydrocortisone replacement therapy | 10 (55.6%) | 8 (33.3%) | 0.470 |
Cortisone acetate replacement therapy | 8 (44.4%) | 16 (66.7%) | 0.174 |
DM/prediabetes No 42 | |||
|---|---|---|---|
Low doses No 18 | High doses No 24 | p | |
Mean ± SD | Mean ± SD | ||
Metabolic parameters | |||
Total cholesterol (mmol/l) | 5.47 ± 0.88 | 5.81 ± 1.37 | 0.419 |
HDL cholesterol (mmol/l) | 1.44 ± 0.52 | 1.46 ± 0.56 | 0.940 |
LDL cholesterol mmol/l) | 3.18 ± 0.73 | 3.28 ± 1.06 | 0.311 |
Triglycerides (mmol/l) | 1.61 ± 0.47 | 1.73 ± 0.65 | 0.744 |
Fasting glucose (mmol/l) | 5.58 ± 4.16 | 7.57 ± 4.51 | 0.174 |
Fasting insulin (UI/ml) | 9.23 ± 6.09 | 14.1 ± 9.8 | 0.294 |
GOT (U/L) | 25.6 ± 19.1 | 21.8 ± 7.71 | 0.601 |
GPT (U/L) | 30.3 ± 15.6 | 23.2 ± 10.5 | 0.542 |
Homa 2-IR | 2.94 ± 2.31 | 1.95 ± 1.21 | 0.216 |
HbA1c (%) | 6.71 ± 1.47 | 7.33 ± 1.66 | 0.165 |
VAI | 2.41 ± 0.82 | 3.06 ± 1.71 | 0.199 |
