Figure 7
Application of the program to iPSC-RPE cell transplantation and CSC images. (a) Quantitative assessment of the Hyperfluorescent areas before and after human iPSC-RPE transplantation in a previously reported case8. The date of iPSC-RPE transplantation surgery was defined as day 0. Upper: A pair of fundus color images. The right image shows the black iPS-RPE-transplanted cells at the center of the image. Middle: A pair of FA images aligned, and brightness corrected by image processing. Lower: Binary images. Yellow frames represent Abnormal regions predicted by U-Net. Green areas represent Hyperfluorescent areas. The Score represents the sum of the pixel numbers of the Hyperfluorescent area in the binarized image. The Growth rate represents the (Test score − Reference score)/Reference score. (b) Application of the program to other diseases with Hyperfluorescent areas and central serous chorioretinopathy (CSC). These images were obtained from two different patients (P1-2). Upper: Pairs of FA images aligned and brightness-corrected by image processing. Lower: Output binary images. Yellow frames represent Abnormal regions (Mask area) predicted by U-net. Green areas represent Hyperfluorescent areas. The Score represents the sum of the pixel numbers of the Hyperfluorescent area in the binarized image within the Mask area. The Growth rate represents the (Test score − Reference score)/Reference score.
