Table 1 Experiment 1 (Visit 1)—fear generalization to imagined stimuli.

From: Mental imagery can generate and regulate acquired differential fear conditioned reactivity

#

k

Brain region

H

Z

MNI

x

y

z

View: CS+ > CS−

1

1001

Frontal orbital cortex, insular cortex, frontal operculum cortex, inferior frontal gyrus pars opercularis

R

4.05

50

10

0

2

934

Thalamus, caudate, putamen, brain stem

R/L

4.30

14

− 16

16

3

652

Paracingulate gyrus, superior frontal gyrus, paracingulate gyrus, supplementary motor cortex

R

4.04

2

28

42

4

467

Insular cortex, frontal orbital cortex, frontal operculum cortex, inferior frontal gyrus pars opercularis

L

3.33

− 26

16

− 14

View: CS− > CS+

1

32,221

Medial frontal, middle frontal and superior frontal gyrus, precentral and postcentral gyrus, posterior cingulate gyrus, inferior, middle and superior temporal gyrus, angular gyrus, lingual gyrus, occipital pole, lateral occipital cortex, hippocampus, amygdala

R/L

6.08

− 4

− 30

62

Imagine: CS+ > CS−

1

1416

Insular cortex, inferior frontal gyrus pars opercularis, frontal operculum, middle frontal gyrus, temporal pole

R

4.03

56

12

6

2

1003

Supramarginal gyrus, angular gyrus, lateral occipital cortex, parietal operculum

R

3.82

58

− 34

44

3

463

Supramarginal gyrus

L

3.68

− 52

− 50

46

Imagine: CS− > CS+

     
  

n.s

     

Interaction: (view CS+ > CS−) > (imagine CS+ > CS−)

  

n.s

 

Interaction: (imagine CS+ > CS) > (view CS+ > CS−)

1

11,338

Precentral and postcentral gyrus; inferior and middle temporal gyrus, angular gyrus, lateral occipital cortex, lateral occipital cortex, hippocampus and amygdala

R/L

4.52

− 18

− 62

64

2

3331

Inferior, middle, and temporal gyrus, angular gyrus, lateral occipital cortex, occipital pole, hippocampus, amygdala

R

3.77

58

− 14

0

3

1739

Superior and middle frontal gyrus, frontal pole

L

4.26

− 30

22

56

4

1293

Supramarginal gyrus

R

4.04

64

− 12

40

5

811

Frontal pole

R

3.98

− 20

60

18

View CS+ > imagine CS+

3

3067

Occipital pole, lateral occipital cortex, fusiform gyrus

L

5.7

− 38

− 78

− 20

2

3041

Occipital pole, lateral occipital cortex, fusiform gyrus, lingual gyrus

R

5.92

34

− 90

2

1

1645

Thalamus, brain stem, caudate

R/L

4.09

8

− 26

− 8

Imagine CS+ > view CS+

1

30,236

Frontal pole, middle frontal gyrus, inferior frontal gyrus, precentral and postcentral gyrus, inferior, middle and superior temporal gyrus, angular gyrus, supramarginal gyrus, superior parietal lobe, occipital pole, latera occipital cortex; hippocampus and amygdala (L), brain stem

R/L

5.73

− 14

− 28

74

2

3548

Superior temporal gyrus posterior division, inferior, middle and temporal gyrus, parahippocampal gyrus, angular gyrus; hippocampus and amygdala

R

4.35

60

− 4

− 2

3

2979

Postcentral and precentral gyrus, supramarginal gyrus, superior parietal lobe, caudate

R

4.33

56

− 4

28

4

504

Lingual gyrus

R/L

3.78

− 12

− 70

− 10

5

406

Frontal pole, paracingulate gyrus

R/L

3.57

12

52

14

  1. # = the number of a cluster, ordered by size; k = the number of contiguous voxels in the cluster; Brain region = regions of local maxima included in the broader cluster. The region names are taken generally from the Harvard–Oxford atlas in FSL; H = principal hemisphere of the cluster, right (R) or left (L); Z = maximum z-value from the cluster within the given brain region; MNI(X,Y,Z) = coordinates of the voxel with the maximum effect in the standardized space of the Montreal Neurological Institute (MNI), represented in units of millimeters (mm). All whole-brain unthresholded group-level maps can be viewed at neurovault.org (see “Methods”).