Figure 3

BMAL1 expression in the hypothalamus predicts the advance of morning activity. mRNA levels of BMAL1 at midnight correlated with the onset (A) and offset of activity (B), but mid-day levels did not (C and D). Shown are log-transformed mRNA levels, separated by ALAN treatments (blue colour gradient). Points represent individual birds, lines and shaded areas represent model fits ± 95% confidence intervals.