Table 2 Crude and adjusted odds ratios of variables associated with mafld.

From: A problem of proportions: estimates of metabolic associated fatty liver disease and liver fibrosis in Australian adults in the nationwide 2012 AusDiab Study

 

MAFLD

No MAFLD

Crude OR (95% CI)

Adj OR (95% CI)

Age (years/OR per 1 year)

61 (54–68)

60 (52–68)

1.01 (1.00–1.01)

1.01 (1.00–1.02)

Male gender (vs female)

58%

37%

2.32 (2.05–2.62)

1.37 (1.17–1.59)

Smoker (vs non-smoker)

6%

5%

1.20 (0.93–1.57)

 

T2 Diabetes (vs no T2DM)

19%

4%

5.43 (4.37–6.76)

3.39 (2.61–4.39)

Systolic BP (mmHg/OR per 10 mmHg)

133 (122–146)

123 (113–137)

1.02 (1.02–1.03)

 

Diastolic BP (mmHg/OR per 10 mmHg)

76 (70–83)

69 (63–76)

1.06 (1.06–1.07)

1.05 (1.05–1.06)

LDL (mmol/L/OR per 1 mmol/L)

3 (2.3–3.7)

3 (2.4–3.6)

1 (0.93–1.07)

 

HDL (mmol/L/OR per 1 mmol/L)

1.3 (1.1–1.5)

1.6 (1.3–1.9)

0.10 (0.09–0.13)

0.15 (0.12–0.19)

ALT elevation

22%

7%

3.57 (2.98–4.28)

3.21 (2.59–3.99)

(≥ 40 IU/L and ≥ 30 IU/L vs no ALT elevation)

    

Exercise

Sufficient

55%

69%

1 (reference)

1 (reference)

Insufficient

29%

23%

1.57 (1.36–1.81)

1.43 (1.21–1.69)

Sedentary

16%

8%

2.34 (1.93–2.83)

1.99 (1.59–2.50)

Post-secondary education (vs primary/secondary education only)

32%

40%

0.72 (0.63–0.81)

0.81 (0.7–0.94)

  1. Multivariable analysis performed by logistic regression examining MAFLD by FLI adjusted for age, gender, diastolic BP, T2DM, HDL cholesterol, ALT elevation, exercise and level of education.
  2. NB: BMI, waist circumference, triglycerides and GGT not included in the model due to collinearity as these variables are included in the FLI diagnostic algorithm.