Table 1 Comparison of baseline characteristics, hemodynamic, echography, and ventilation parameters, at baseline and after the first fluid challenge of 250 ml, between responding and non-responding patients.

From: Assessment of fluid unresponsiveness guided by lung ultrasound in abdominal surgery: a prospective cohort study

Characteristics

Responders (n = 133)

Non-responders (n = 64)

p-values

Age; years

61 [47–70]

62 [48–71]

0.88

Female sex (%)

59 (44%)

26 (40%)

0.28

ASA-PS score

2 [2–3]

2 [2–3]

0.25

BMI; kg m−2

25 [22–29]

27 [22–31]

0.29

Medical background (%)

Arterial hypertension

58 (44%)

23 (36%)

0.26

Myocardial infarction

7 (5%)

5 (8%)

0.41

Cardiac dysfunction

2 (2%)

0

0.26

OSAS

10 (8%)

4 (6%)

0.25

Smoking

23 (17%)

8 (13%)

0.47

Arteritis

4 (3%)

0

0.16

Stroke

8 (6%)

3 (5%)

0.78

Diabetes

23 (17%)

12 (19%)

0.73

Dyslipidemia

28 (21%)

11 (17%)

0.50

Chronic renal disease

7 (5%)

4 (6%)

0.77

HR; min−1

Baseline

69 [61–81]

73 [63–81]

0.61

250 ml

66 [58–80] *

71 [68–80]

0.04

MAP; mmHg

Baseline

70 [64–78]

75 [65–82]

0.10

250 ml

69 [63–79]

75 [68–83]

< 0.01

Cardiac index; l min−1 m−2

Baseline

2.5 [2.0–3.2]

2.8 [2.3–3.3]

0.08

250 ml

2.9 [2.3–3.5]*

2.7 [2.2–3.5]

0.54

SpO2; %

Baseline

99 ± 1

98 ± 2

0.03

250 ml

99 ± 1

98 ± 2

< 0.01

Total B-lines

Baseline

0 [0–1]

0 [0–4]

< 0.01

250 ml

1 [0–3]*

4 [2–7]*

< 0.01

Minute ventilation; l min−1

6.3 [5.6–7.1]

6.4 [6.0–7.1]

0.30

PEEP; cmH2O

5 [5–6]

5 [5–6]

0.76

Plateau pressure; cmH2O

17 [15–19]

17 [15–19]

0.98

  1. Significant values are in bold.
  2. Values are means ± SD, numbers (proportion) or median [IQR].
  3. ASA-PS American Society of Anesthesiology-Physical status, BMI body mass index, HR heart rate, MAP mean arterial pressure, OSAS obstructive sleep apnea syndrome, SpO2 pulsed oxygen saturation, PEEP positive end-expiratory pressure. The p-value refers to the intergroup comparison. *p < 0.05 for the intragroup effect.
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