Figure 5
From: Addressing cancer invasion and cell motility with quantitative light microscopy
Example images from a time-lapse recording with control A549 cells: (a) time point 0 h and (b) time point 10 h. The field size is 634 × 483 µm. The pseudo-color bar represents a range of dry-mass densities from 0 to 2.7 pg µm−2. (c) Growth curves illustrate the increase in dry-mass of cells and clusters in the recording. (d) Box and whisker plot of the mass doubling time showing a significant reduction in growth—extended doubling time, with GDC in comparison to CNT and DMSO. GSK achieved a smaller reduction, only significant in comparison to DMSO. Dots represent medians, boxes span 50% of the data, whiskers span the full range of data, and outliers are shown as open circles.
