Table 1 In vitro fertilisation experiments.
Genotype | Treatment | Oocyte co l lection | Fertilisation and embryo development | |||||
|---|---|---|---|---|---|---|---|---|
Mouse ID | # Total | # Degenerated | # 2-cell embryos | % Fertilisation | # Blastocysts | % Blastocysts | ||
Brip1+/- | Carboplatin + Paclitaxel | F41 | 11 | 0 | 2 | 18.2 | 0 | 0.0 |
F4 | 0 | 0 | 0 | 0.0 | 0 | 0.0 | ||
F1 | 14 | 0 | 4 | 28.6 | 2 | 50.0 | ||
F3 | 1 | 0 | 0 | 0.0 | 0 | 0.0 | ||
F14 | 14 | 1 | 6 | 46.2 | 2 | 33.3 | ||
Summary | 40a | 1 | 12 | 30.8 b | 4 | 33.3b | ||
Control | F4 | 35 | 0 | 18 | 51.4 | 10 | 55.6 | |
F43 | 43 | 1 | 20 | 47.6 | 11 | 55.0 | ||
F4 | 26 | 3 | 12 | 52.2 | 8 | 66.7 | ||
F1 | 28 | 5 | 16 | 69.6 | 10 | 62.5 | ||
F3 | 26 | 4 | 18 | 81.8 | 8 | 44.4 | ||
Summary | 158 | 13 | 84 | 57.9 | 47 | 56.0 | ||
Brip1+/+ | Carboplatin + Paclitaxel | F3 | 4 | 0 | 0 | 0.0 | 0 | 0.0 |
F10 | 0 | 0 | 0 | 0.0 | 0 | 0.0 | ||
F10 | 16 | 1 | 2 | 13.3 | 0 | 0.0 | ||
F31 | 21 | 6 | 1 | 6.7 | 0 | 0.0 | ||
F33 | 12 | 0 | 8 | 66.7 | 4 | 50.0 | ||
Summary | 53 b | 7 | 11 | 23.9a | 4 | 36.4b | ||
Control | F44 | 30 | 5 | 16 | 64.0 | 8 | 50.0 | |
F10 | 28 | 4 | 14 | 58.3 | 8 | 57.1 | ||
F1 | 17 | 2 | 10 | 66.7 | 6 | 60.0 | ||
F41 | 47 | 1 | 28 | 60.9 | 18 | 64.3 | ||
F1 | 30 | 5 | 14 | 56.0 | 6 | 42.9 | ||
Summary | 152 | 17 | 82 | 60.7 | 46 | 56.1 | ||
