Table 1 Patients’ demographics and clinicopathological characteristics.
Total | Non-chemotherapy | Chemotherapy | Characteristics | p value | SMD |
|---|---|---|---|---|---|
(n = 1092) | (n = 546) | (n = 546) | |||
Age at diagnosis, n (%) | 0.425 | 0.079 | |||
< 59 years | 504 (46) | 260 (47) | 244 (45) | ||
59–66 years | 347 (32) | 174 (32) | 173 (32) | ||
66–74 years | 241 (22) | 112 (21) | 129 (23) | ||
Sex, n (%) | 0.882 | 0.013 | |||
Female | 229 (21) | 113 (21) | 116 (21) | ||
Male | 863 (79) | 433 (79) | 430 (79) | ||
Race, n (%) | 0.972 | 0.014 | |||
White | 736 (68) | 369 (68) | 367 (67) | ||
Black | 155 (14) | 78 (14) | 77 (14) | ||
Other | 201 (18) | 99 (18) | 102 (19) | ||
AJCC, n (%) | 0.675 | 0.075 | |||
I | 426 (39) | 207 (38) | 219 (40) | ||
II | 389 (36) | 204 (38) | 185 (34) | ||
III | 185 (17) | 89 (16) | 96 (18) | ||
IV | 92 (8) | 46 (8) | 46 (8) | ||
Grade, n (%) | 0.823 | 0.058 | |||
Well differentiated | 346 (32) | 171 (31) | 175 (32) | ||
Moderately differentiated | 551 (50) | 272 (50) | 279 (51) | ||
Poorly differentiated | 183 (17) | 96 (18) | 87 (16) | ||
Undifferentiated | 12 (1) | 7 (1) | 5 (1) | ||
Tumor size, n (%) | 0.889 | 0.029 | |||
< 3.5 cm | 504 (46) | 255 (46) | 249 (46) | ||
3.5–7.2 cm | 368 (34) | 184 (34) | 184 (33) | ||
> 7.2 cm | 220 (20) | 107 (20) | 113 (21) | ||
AFP, n (%) | 0.429 | 0.052 | |||
Negative | 331 (30) | 159 (29) | 172 (32) | ||
Positive | 761 (70) | 387 (71) | 374 (68) | ||
Fibrosis score, n (%) | 0.667 | 0.03 | |||
F0 | 253 (23) | 130 (24) | 123 (23) | ||
F1 | 839 (77) | 416 (76) | 423 (77) | ||
Radiotherapy, n (%) | 1 | 0.006 | |||
No | 993 (91) | 496 (91) | 497 (91) | ||
Yes | 99 (9) | 50 (9) | 49 (9) | ||
Surgery, n (%) | 0.914 | 0.044 | |||
No surgery | 444 (41) | 219 (40) | 225 (41) | ||
Hepatectomy | 213 (20) | 108 (20) | 105 (19) | ||
Hepatectomy and transplant | 298 (27) | 153 (28) | 145 (27) | ||
Others | 137 (12) | 66 (12) | 71 (13) | ||
Survival times, Median (IQR) | 23.00 (11.00, 45.00) | 22 (7.00, 46.75) | 23.00 (13.00, 43.00) | 0.017* |
