Figure 2
From: Epigenetic study of early breast cancer (EBC) based on DNA methylation and gene integration analysis
Analysis of differential methylation sites. (A) PCA of methylation sites; (B) The distribution of the β value of the sample; (C) Heat map of top 200 DMSs. Complete‑linkage method combined with Euclidean distance is used to construct clustering. Each row represents DMSs, and each column represents a sample. DMSs clustering tree is shown on the left. Red indicates above the reference channel (high expression genes). Blue indicates below the reference channel (low expression genes); (D) The Manhattan figure of DMSs in chromosome. The x-axis and y-axis represents the chromosomeand and the -log10 (FDR) of DMSs, respectively.
