Table 2 Predictive factors at pre-treatment for occurrence of HCC after SVR.

From: Prediction of hepatocellular carcinoma using age and liver stiffness on transient elastography after hepatitis C virus eradication

Factors

Cut-off value

Univariate p values

Multivariate

HR

95% CI

p-values

Sex

Male

0.185

   

Age (years old)

 ≥ 71

0.004

3.402

1.447–8.001

0.005

BMI (kg/m2)

 ≥ 25

0.097

   

HCV genotype

1

0.289

   

Diabetes

Yes

0.029

1.479

0.653–3.351

0.349

Therapy resume; SOF based

Yes

0.206

   

Pre platelet (× 104/µl)

 ≥ 13.2

0.004

–

  

Pre ALT (IU/L)

 ≥ 40

0.810

   

Pre albumin (g/dl)

 ≥ 3.9

0.011

1.419

0.621–3.245

0.407

Pre AFP (ng/ml)

 ≥ 6.2

0.002

2.400

0.957–6.017

0.062

Pre FIB4 index

 ≥ 3.25

0.023

0.541

0.201–1.460

0.296

Pre LSM (kPa)

 ≥ 9.2

 < 0.001

6.328

2.205–18.160

 < 0.001

Pre CAP (db/m)

 ≥ 230

0.106

   
  1. BMI Body mass index, HCV Hepatitis C virus, SOF Sofosbuvir, Pre Pre-treatment, AST Aspartate transaminase, ALT Alanine aminotransferase, GGT γ-glutamyltransferase, AFP α-fetoprotein, LSM Liver stiffness measurement, CAP Controlled attenuation parameter.
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