Figure 4 | Scientific Reports

Figure 4

From: Intranasal calcitonin gene-related peptide administration impairs fear memory retention in mice through the PKD/p-HDAC5/Npas4 pathway

Figure 4

Intranasal CGRP attenuates fear memory retention via the CGRP receptor with an increase in Npas4 expression. (A) Effects of CGRP receptor antagonist BIBN4096 (1 mg/kg) on fear memory retention. (B) Effects of BIBN4096 on the levels of Npas4 protein expression. Each bar indicates the mean ± S.E.M. *p < 0.05, Tukey–Kramer test. Numbers in parentheses indicate the animal numbers for each group.

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