Table 3 Results of colocalisation analyses for RHOD and CDC42 genes.

From: Rho GTPase gene expression and breast cancer risk: a Mendelian randomization analysis

 

Overall breast cancer

ER+ breast cancer

ER− breast cancer

RHOD (GTEx)

PP Hypothesis0

4.68 × 10–10

2.29 × 10–11

9.26 × 10–9

PP Hypothesis1

0.04

0.002

0.85

PP Hypothesis2

9.63 × 10–10

1.98 × 10–10

6.77 × 10–10

PP Hypothesis3

0.09

0.02

0.06

PP Hypothesis4

0.87

0.98

0.09

CDC42 (eQTLGen)

PP Hypothesis0

9.36 × 10–306

1.78 × 10–305

2.54 × 10–305

PP Hypothesis1

0.33

0.62

0.89

PP Hypothesis2

3.42 × 10–306

3.15 × 10–306

3.05 × 10–306

PP Hypothesis3

0.12

0.11

0.11

PP Hypothesis4

0.55

0.27

0.007

  1. nsnp number of SNPs used in the analysis, PP posterior probability.
Back to article page