Table 4 Drug-likeness properties of synthesized compounds.
Compound | MW | Num. rotatable bonds | Num. H-bond acceptors | Num. H-bond donors | Log P |
|---|---|---|---|---|---|
8a | 439.478 | 6 | 9 | 1 | 3.4812 |
8b | 473.923 | 6 | 9 | 1 | 4.1346 |
8c | 518.374 | 6 | 9 | 1 | 4.2437 |
8d | 469.504 | 7 | 10 | 1 | 3.4898 |
8e | 405.461 | 7 | 9 | 1 | 2.902 |
8f | 467.532 | 7 | 9 | 1 | 3.8487 |
8g | 454.493 | 7 | 10 | 1 | 2.9353 |
8h | 469.548 | 8 | 10 | 3 | 3.4113 |
8i | 405.461 | 7 | 9 | 1 | 2.902 |
8j | 405.461 | 6 | 9 | 1 | 3.0729 |
8k | 419.488 | 8 | 9 | 1 | 3.2921 |
8l | 405.461 | 6 | 9 | 1 | 3.0729 |
8m | 403.445 | 7 | 9 | 1 | 2.678 |
8n | 431.499 | 6 | 9 | 1 | 3.6071 |
